glycerol phenylbutyrate will reduce the level or impact of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Glycerol phenylbutyrate is really a weak inducer of CYP3A4. Check for reduced efficacy of CYP3A4 substrates which have a slim therapeutic index.Tolerance to estazolam might establish from continued ther